MI-2 (Menin-MLL Inhibitor)

CAS No. 1271738-62-5

MI-2 (Menin-MLL Inhibitor) ( Menin-MLL Inhibitor )

Catalog No. M11137 CAS No. 1271738-62-5

MI-2 (Menin-MLL Inhibitor) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 53 In Stock
5MG 87 In Stock
10MG 140 In Stock
25MG 257 In Stock
50MG 435 In Stock
100MG 622 In Stock
200MG 885 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    MI-2 (Menin-MLL Inhibitor)
  • Note
    Research use only, not for human use.
  • Brief Description
    MI-2 (Menin-MLL Inhibitor) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.
  • Description
    MI-2 (Menin-MLL Inhibitor) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.
  • Synonyms
    Menin-MLL Inhibitor
  • Pathway
    Chromatin/Epigenetic
  • Target
    HMTase
  • Recptor
    Menin-MLL
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1271738-62-5
  • Formula Weight
    375.55
  • Molecular Formula
    C18H25N5S2
  • Purity
    >98%(HPLC)
  • Solubility
    Ethanol: 75 mg/mL (199.7 mM); DMSO: 75 mg/mL warmed (199.7 mM)
  • SMILES
    CCCC1=CC2=C(N3CCN(C4=NCC(C)(C)S4)CC3)N=CN=C2S1
  • Chemical Name
    4-[4-(5,5-dimethyl-4H-1,3-thiazol-2-yl)piperazin-1-yl]-6-propylthieno[2,3-d]pyrimidine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Grembecka J, et al. nat Chem Biol. 2012, 8(3), 277-284.
molnova catalog
related products
  • UNC0379

    UNC0379 is a selective, substrate-competitive inhibitor of lysine methyltransferase SETD8 with IC50 of 7.3 uM.

  • UNC1215

    A potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3 with Kd of 120 nM.

  • GSK503

    GSK503 is a potent, specific EZH2 methyltransferase inhibitor that inhibits the methyltransferase activity of WT and mutant EZH2 with similar potency (Ki app=3-27 nM).